Important pathological changes in hair follicle tumor
a central for the expansion of the primary hair follicle cystoid around for the radial array of secondary follicles,
b secondary follicles surrounded by obvious fibrous sheath around the hair root follicles the central primary.
General pathological changes
A tumor located in the dermis, symmetry, border clearance,
b lesions and distortion of the central authorities for the expansion of the primary hair follicle, associated with the epidermis,
c primary keratinocytes and hair follicles have the majority of hair dry,
d secondary follicles mature, can be seen within the hair root sheath, outer hair root sheath, fibrous hair root sheath, dermal papilla and hair ball
e secondary follicles connected by the Piso, Piso and the surrounding secondary follicles surrounded by fibrous stroma,
f tumor cells was significantly heterogeneous; isthmic keratinization composition, with light staining cytoplasm and around the cells were arranged in palisade-like outer hair root sheath cells and dense polygon or Pilomatrixoma basaloid cells.
Pathological differential diagnosis
Trichoepithelioma: no expansion of the central primary follicles, the tumor cells mainly basaloid tumor cells rather than a variety of hair follicle cells, there is no hair dry.
Clinical features
A mostly adult males,
b occurred in the face, especially the nose, followed by head and neck,
c damage often single for a higher surface of the skin papules or nodules, about 4mm in diameter, the central concave have umbilical, which are clustered across the vellus hair.
Alias
Hair follicle tumors (Follicular epithelioma)