Tumors of the impact of the body
Benign and malignant tumors because of their different effects on the body's different.

Benign: differentiation of their more mature, slow growth, stop at the local, non-invasive, non-shifting of the general body of the impact of relatively small, mainly local oppression and obstruction symptoms. Its impact on the occurrence of major and secondary to its location changes. In addition to the body surface, such as benign tumors can occur a few local symptoms, generally without a significant impact on the body; but occurred in the cavity Road or vital organs, can cause more serious consequences, such as benign digestive tract (such as the intestine into the Leiomyoma), and sometimes cause intussusception, or bowel obstruction; a benign brain tumor (such as meningioma, astrocytoma) can block the brain ventricles of oppression caused by intracranial pressure system and the nervous system symptoms . Sometimes benign tumors can occur secondary to change, can also bring different levels of the body, such as the intestinal adenomatous polyposis, bladder, and so on the surface of the papilloma may occur and cause bleeding ulcers and infection. In addition, the endocrine gland is often a result of the benign tumor can cause some kind of hormone secretion and generate too many systemic effects, such as the anterior pituitary adenoma eosinophilic (acidophil adenoma) can cause gigantism (gigantism) or acromegaly ( acromegaly); islet cell tumor secreting too much insulin, which can cause low blood sugar, such as paroxysmal.

Cancer: cancer due to the secretion of immature, rapidly growing, invasive organ damage to the structure and function, and the transfer took place, thus seriously affect the body. In addition to the malignant tumors can be caused by benign tumors similar to the above-mentioned local oppression and obstruction symptoms, occur in the digestive tract are more complicated ulcers, bleeding or even perforation, leading to peritonitis, the more serious consequences. Sometimes the product of the tumor or infection can cause fever. Tumor-infiltrating, the local nerve compression can also cause symptoms such as intractable pain. Patients with advanced malignant tumors often occur cachexia (cachexia), can be caused by the death of patients. Cachexia refers to the serious body weight loss, weakness, anemia and systemic failure of the state, the mechanism has not yet entirely clear, perhaps because of the lack of appetite, eating less bleeding, infection, fever or tumor necrosis produced by the body caused by toxic products, such as the Due to metabolic disorders. In addition, the rapid growth of malignant tumors, the consumption of large amount of nutrients the body, as well as late as a result of the pain caused by cancer, the impact on patients, such as eating and sleeping, but also lead to cachexia an important factor. In recent years, found that macrophages produced tumor necrosis factor (TNF) reduces appetite and increases catabolism, cachexia and the occurrence of a certain relationship.

In recent years, have been found in some non-endocrine tumors produce and secrete hormones, or hormones material, such as adrenocorticotropic hormone (ACTH), parathyroid hormone (PTH), insulin, antidiuretic hormone (ADH), and promoting human chorionic gonad Hormone (HCG), thyroid stimulating hormone (TSH), growth hormone (GH), calcitonin (calcitonin), and so on more than 10 species can be caused by endocrine disorder symptoms. Ectopic endocrine tumors such as the tumor, it caused the clinical symptoms of ectopic known as endocrine syndrome. Such as malignant tumors, most of which was to cancer, such as lung cancer, gastric cancer, liver cancer, pancreatic cancer, colon cancer, and so on; also can be found in sarcoma, such as fibrosarcoma, leiomyosarcoma, rhabdomyosarcoma, and undifferentiated sarcoma, and so on. Many ectopic secretion of the hormone are two kinds of cancer than the characteristics of the hormone. With regard to ectopic hormone produced by this mechanism is no consistent explanation may be related to tumor cells with abnormal expression of genes. In addition to the above ectopic endocrine syndrome, due to the tumor or a product of the abnormal immune response (including cross-immunity, autoimmune and immune complexes calm, and so on) or other unknown causes, can also be caused by nerves, digestive, blood, bones and joints, kidneys and Some systems, such as skin lesions and clinical performance. These are not the performance of the original tumor metastasis, or the site where the direct cause, but through the above channels indirectly caused, it is known syndromes (paraneoplastic syndrome). These can sometimes syndrome was very clear and serious consequences. Recognizing the significance of this syndrome is that it may be hiding some of the early performance of the tumor, which can be found early tumors. Moreover, these systems do not mistake the change is due to tumor metastasis, and give up on the treatment of tumors. In contrast, if the effective treatment of tumors, which reduce the syndrome, or disappear. There is a very important clinical significance.