Xanthoma xanthoma
Xanthoma
A rare disease of lipid metabolism. Containing lipid as a result of the cells in the dermis or subcutaneous tissue together with the often formed on the surface of the skin tumor-like yellow damage, named. Disease patterns and the distribution of a variety of skin rashes. There are nodular, flat and eruptive and 4 types of tendon. The disease can be combined abnormal lipid metabolism. Some cases are familial, and some systemic diseases, such as lipid deposition in atherosclerosis can produce cardiovascular and thrombosis of small blood vessels. Some can also be combined or secondary to other diseases such as diabetes, liver disease, kidney disease. Yellow skin tumors when found, the first should be simple to determine their skin type or skin Hyperlipoproteinemia performance. Not only damage the skin offal violation cases, the general prognosis is good.
There are common xanthoma following: ① eyelid xanthoma. Bureau of skin damage limited to a small patch of soft, diameter of about 0.5 ~ 1 cm, state clearly that higher out of the skin surface, symmetrical distribution of the upper eyelid in the Department of inner canthal, and sometimes incidence of upper and lower eyelids can be. Was particularly prevalent in middle-aged women. Incidence after the age of 40 are generally normal blood lipoprotein. 40 years ago and have a family history of morbidity, and often accompanied by increased blood cholesterol and early atherosclerosis. ② tuberous xanthoma. Lesions yellow or orange-red papules and nodules, the distribution of joints in the extremities and the extensor side of the oppressed and the friction-prone areas, such as肘膝, hip, hand, foot and back, such as the palm of your hand. Mucosa may also be affected, blood lipoprotein increased, sometimes associated with biliary cirrhosis, edema of the skin mucus. ③ tendon xanthoma. Attached to the tendon, ligament, fascia, 0.5 ~ 2.5 cm in diameter, quality hardware, good fat in the achilles tendon, hand, foot and back tendon, the tendon can be with the activity, often a family history. Increased serum LDL can lead to cardiovascular and lipid deposition in liver and gallbladder, and cause the performance of the corresponding systemic. ④ disseminated xanthoma. Rare. ⑤ juvenile xanthogranuloma. A benign, self-limiting yellow-brown papules or nodules. Often at birth or appear within one year after birth, multiple, 12 to 18 months of spontaneous regression. Can occur in a small number of eyes, lungs, pericardium, meninges, liver, spleen, etc..
Therapy should be the first to find the reasons for lipid metabolism disorders, such as diet, genetics, diabetes, etc., to be aimed at correcting the cause. Too much weight should reduce the weight to regulate the diet, into the low-fat, low energy, low-cholesterol diet, and the application of hypolipidemic drugs. When the plasma lipids returned to normal when the rash may subside within a few weeks. Large nodules removed by surgery, the skin damage can be fulguration.